Hereditary spastic paraplegia (HSP; also known as hereditary spastic paraparesis, Strumpell disease, Striimpell- Lorrain disease, hereditary Charcot disease, hereditary progressive spastic paraplegia, and French settlement disease) is a label used to represent a group of inherited degenerative spinal cord disorders characterized by a slow, gradual, progressive weakness and spasticity (stiffness) of the legs.