Amphetamines are stimulants to the central nervous system. Their effect is similar to that of the body’s own adrenaline. Even though amphetamines mimic the effects of adrenaline, they act for a much longer time in the body. Illicit synthesis and use of methamphetamine is the chief type of amphetamine abuse in North America. Although they are available by prescription, amphetamines are no longer used as appetite suppressants and infrequently used for other conditions. An amphetamine psychosis is similar to paranoid schizophrenia. It occurs when the person misinterprets others’ actions, hallucinates, and becomes unrealistically suspicious. After the stimulation phase, individuals experience intense fatigue, a need for sleep, and a prolonged depression, during which suicide is possible. The psychosis results from long-term use of high IV doses but can result from high oral doses.