Infection and inflammation of the outer layers of skin, predominantly but not exclusively found in children, elderly persons, and immunosuppressed patients. It is caused by exotoxins produced by Staphylococcus aureus. Initially, the skin in the affected areas is rough, with a bright red, flat rash; it then becomes wrinkled, and blisters form. The syndrome is treated with antistaphylococcal antibiotics (e.g., nafcillin), and supportive care is provided to minimize the risk of cellulitis or pneumonia. About 2% to 3% of affected patients die of the disease. In survivors, the blisters heal without scarring.
A condition induced by Staphylococcus aureus, characterized by the potential detachment of extensive layers of skin from the body, primarily tends to impact infants, young children, and individuals with compromised immune systems.