A hydroxylated form of the imino acid proline. A deficiency in ascorbic acid can result in impaired hydroxyproline formation.
Amino acid found mainly in connective tissue proteins (collagen and elastin); incorporated into the protein as proline and then hydroxylated in a vitamin C-dependent reaction. Peptides of hydroxyproline are excreted in the urine and the output is increased when collagen turnover is high, as in rapid growth or resorption of tissue.
An amino acid present in some proteins, especially in collagen.
Elevated levels are found in the urine in bone disease and certain inherited conditions such as Marfan’s syndrome.
A compound, similar in structure to the amino acids, found only in collagen.