Lipoprotein that contains most of the cholesterol in the blood. LDL carries cholesterol to the tissues of the body, including the arteries. A high level of LDL increases the risk of heart disease. LDL typically contains 60 to 70 percent of the total serum cholesterol and both are directly correlated with CHD risk.
LDL carry cholesterol and triglycerides from the liver to the tissues. It is the cholesterol in LDL that finds its way into the plaques of atherosclerosis, and LDL cholesterol has been dubbed the “bad cholesterol.”
Is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. High levels of LDL cholesterol can signal medical problems like cardiovascular disease, and it is sometimes called “bad cholesterol”.
Low-density lipoproteins; manufactured in the liver, they circulate throughout the body, making their fat available to all body cells; contain 45% cholesterol.
A lipoprotein in blood plasma composed of protein, a small portion of triglyceride, and a large portion of cholesterol whose purpose is to transport cholesterol to the cells.
So-called “bad” cholesterol, which carries cholesterol molecules from the digestive system (e.g., intestine) to body cells and can clog arteries over time (a disease called atherosclerosis, or coronary heart disease). Since cholesterol does not dissolve in water (which constitutes most of the volume of blood), the body makes LDL cholesterol (derived from the digestion of fatty foods) into little “packages” surrounded by a hydrophilic protein. That protein “wrapper” is known as apolipoprotein B-lOO, or apo B-lOO, and it enables LDL cholesterol to be transported in the bloodstream because the apolipoprotein B-lOO is attracted to water molecules in the blood. Part of the apolipoprotein B-lOO molecule also will bind to special LDLP receptor molecules in the liver, which then clears those (bound) cholesterol packages out of the body as part of regular liver functions.
A protein and lipid molecule that is manufactured in the liver and transferred to the bloodstream. LDL delivers cholesterol to tissues and has been implicated in the accumulation of plaque within the arteries. Often referred to as “bad” cholesterol.
The part of serum cholesterol that tends to accumulate in the walls of arteries, contributing to the development of atherosclerosis high-density lipoprotein (HDL).
A lipoprotein with a large percentage of cholesterol which deposits fats in muscles and arteries.
A lipid protein complex consisting of a carrier protein, triglycerides, and cholesterol. Elevated LDL levels are associated with an increased risk of coronary vessel disease.
Low density lipoproteins are within a group of complexes of lipids and proteins that are particularly rich in cholesterol. Their primary function is cholesterol transport. LDL particles are produced in the catabolism of VLDL by the action of lipoprotein lipase. VLDL are transiently converted to intermediate density lipoproteins (IDL) during this process.
A fraction of blood fat that tends to promote lipid (fatty) deposits in tissues and blood vessels, which may lead to clogging of the vessels and cause cardiovascular disease.
Plasma lipids that carry the majority of the cholesterol in plasma. Bound to albumin, LDLs are a proven cause of atherosclerosis; lowering LDLs with a low-fat diet or with drugs helps to prevent and treat coronary artery disease.
Low-density lipoprotein is considered the bad form of cholesterol because it more easily attaches to the blood vessel wall, thereby increasing the atherosclerotic process.
Carries cholesterol from the liver to the rest of the body. When there is too much LDL cholesterol in the blood, it can be deposited on the walls of the coronary arteries. It is often referred to as bad cholesterol.
In the realm of lipid metabolism, a specific class of lipoprotein plays a crucial role in transporting cholesterol throughout the bloodstream. This particular lipoprotein is commonly referred to as LDL cholesterol and has gained the reputation of being “bad” due to its potential to contribute to the development of atherosclerosis, a condition closely associated with cardiovascular disease. Understanding the role and impact of LDL cholesterol aids in recognizing its significance in maintaining cardiovascular health and the potential risks it poses when imbalances occur.