Seroconversion

The development of antibodies (specific to that diseasecausing microorganism) in response to vaccination or natural exposure to a disease-causing microorganism.


Development of detectable specific antibodies to a disease-causing organism or vaccine.


Process where exposure to a pathogen causes a change from negative to a positive finding of antibodies for that pathogen; often observed with tuberculosis.


A positive result for an infection in a blood test that at some earlier point in time showed a negative result for the same test.


The production of specific antibodies to antigens present in the body. This may happen as a result of infection by a virus, or immunization with a VACCINE. Thus, if blood has been tested before the event there may be little or no evidence of antibody to the condition in question; but when a sample is taken 1-2 weeks later there may be a high level of antibody confirming that recent infection has taken place. Sometimes this is the only way to prove that a particular infection has occurred or that a vaccination has ‘taken’. One example of its value would be if a woman in early pregnancy thought she might have encountered RUBELLA (German Measles) which can damage the fetus. If she fails to seroconvert then she has not been infected by the virus so no action is necessary or advisable.


The development of an antibody response to an infection or vaccine, measurable in the serum.


The production of identifiable antibodies in a patient’s blood serum occurs in response to infection or immunization, enabling their detection in specific and targeted assays.


The formation of antibodies in the blood serum, which are proteins specifically designed to fight a particular infection, can be identified through diagnostic tests.


 


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