Somatostatin

A 14 amino acid peptide that inhibits the release of growth hormone.


A hormone produced in the hypothalamus which helps to prevent the release of the growth hormone.


Hormone released by D cells of pancreatic islets and other organs (intestine, brain, etc.); serves as an appetite suppressant.


A peptide responsible for the regulation and inhibition of hormones by various neuroendocrine cells in the brain and gastrointestinal tract.


Also known as the growth-hormone-release inhibiting factor, this is a hormone secreted by the hypothalamus and some non-nervous tissues (including the gastrointestinal tract and pancreas). It stops the pituitary from releasing somatotrophin growth hormone. Somatostatin and growth-hormone-releasing hormone are controlled by complicated neural mechanisms linked to exercise, sleep patterns, stress, neurotransmitters and blood glucose.


A peptide that regulates and inhibits the release of hormones by many different neuroendocrine cells in the brain, pancreas, and gastrointestinal tract. Somatostatin inhibits gastric motility and gastric acid secretion, blocks the exocrine and endocrine function of the pancreas, and inhibits the growth and release of hormones by neuroendocrine tumors. It is also used to treat variceal hemorrhage in patients with cirrhosis and to treat pancreatitis. Octreotide is a synthetic version of somatostatin.


 


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