A high molecular weight glycoprotein composed of three polypeptide chains that are organized in a cross‐like manner; functional domains of this molecule have affinity for cell surface receptors and extracellular matrix components.
Large, non-collagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
A glycoprotein found in all basement membranes that is involved in the binding of cells to the extracellular matrix, particularly to type intravenous collagen. It contributes to the growth and cellular organization of tissues and is involved in angiogenesis, invasion, and metastasis of tumor cells, and cellular attachment.