Characterized by a progressive deterioration of a tissue or tissues resulting in a reduction in the ability to function, chronic disease, acute disease.
A disease or disorder in which there is progressive loss of function of a part of the body, or in which a part of the body fails to repair itself.
An illness resulting from aging, repetitive injury, or other pathologic causes.
A disease in which the function or structure of the affected tissues or organs changes for the worse over time. Osteoarthritis, osteoporosis and Alzheimer’s disease are examples.