Achlorhydria

Deficiency of hydrochloric acid in gastric digestive juice.


The lack of free hydrochloric acid  in the stomach; more broadly, inadequate or suppressed secretions. The cause vary from stomach ulcers, alcoholism, adrenalin stress, and old age to a stomach carcinoma. Without enough acid, pepsin is inactive, proteins are poorly digested, and the prolonged contact with foreign, intact proteins increases food sensitivities in the upper intestinal mucosa.


Absence of hydrochloric acid in the stomach either through gastric cell malfunction or through the surgical removal of the acid-producing cells in this organ. Iron absorption is impaired in this condition as is the conversion of pepsinogen to pepsin, a proteolytic enzyme important for protein digestion.


A condition in which the gastric juices do not contain hydrochloric acid, a symptom of stomach cancer or pernicious anaemia.


Abnormal condition characterized by the absence of hydrochloric acid in the gastric juice, often associated with pernicious anemia, other severe anemias, and cancer of the stomach, achlorhydric.


Absence of hydrochloric acid in the stomach. Achlorhydria that persists despite large doses of histamine is associated with atrophy of the lining (mucosa) of the stomach. In this condition there may be an absence of secretion of ‘intrinsic factor, which will lead to ‘pernicious anemia. In some people, however, achlorhydria is not associated with any disease, produces no ill-effects, and needs no treatment.


Absence of free hydrochloric acid in the stomach; may be associated with gastric carcinoma, gastric ulcer, pernicious anemia, adrenal insufficiency, or chronic gastritis.


It refers to an atypical state characterized by the absence of hydrochloric acid in the secretions produced by the gastric glands within the stomach.


The lack of secretion of stomach acid is characterized by the absence of acid production in the gastric environment. This condition can be attributed to chronic atrophic gastritis or to the absence or impaired functioning of the parietal cells responsible for acid production in the lining of the stomach.


Achlorhydria, although often asymptomatic and not inherently worrisome, can be linked to stomach cancer and is also observed in pernicious anemia, a blood disorder characterized by impaired absorption of vitamin B12 from the stomach.


 


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