Enzyme found in high concentrations in osteoblasts; commonly located on cytoplasmic processes extending into the osteoid. The level of alkaline phosphatase in serum is a systemic indicator for bone formation.
A blood test used to measure an enzyme to determine the presence of skeletal diseases and certain types of liver diseases.
An enzyme in the cells lining the biliary ducts of the liver. ALP levels in plasma will rise with large bile duct obstruction, intrahepatic cholestasis or infiltrative diseases of the liver. ALP is also present in bone and placental tissues.
An enzyme whose optimal pH is about 9.8. It is present in the fiver, kidneys, intestines, teeth, plasma, and developing bone. Alkaline phosphatase levels greater than 300% of normal usually signify cholestatic disorders like obstructive jaundice or intrahepatic biliary disease.
Throughout the entirety of the organism, there exists an enzyme that is predominantly present in vital organs such as the liver, skeletal system, placenta, and the intricate intestinal network.
An enzyme that accelerates the splitting of orthophosphate in acidic conditions.