Angiogenesis

The physiologic process of growth and proliferation of new blood vessels from preexisting vasculature. The process occurs throughout life, in both health and disease, and plays a vital role in growth, development, and wound healing.


A physiological process involving the growth of new blood vessels from preexisting vessels.


Formation/development of new blood vessels in the body. Discovered to be triggered and stimulated by Angiogenic Growth Factors, in the early 1980’s. Angiogenesis is required for malignant tumors to metastasize (spread throughout the body), because it provides the (newly created) blood supply that tumors require. Angiogenesis is also crucial to the development of glaucoma and macular degeneration (major cause of blindness). The drug Thalidomide is a potent inhibitor of angiogenesis.


The formation of new blood vessels, e.g. in an embryo or as a result of a tumour.


Development of blood vessels; leptin stimulates angiogenesis in the adipose tissue, thereby increasing its blood supply.


The growth of new blood vessels. Chemicals produced by cancers may stimulate angiogenesis. Some evidence suggests that angiogenesis may be necessary for cancers to grow or spread. Researchers are investigating new cancer therapies using angiogenesis inhibitors to prevent the formation of new blood vessels in cancerous tumors.


An intense, noninflammatory swelling of the skin, organs, and brain, potentially accompanied by fever and muscle discomfort.


A radiographic image of a blood vessel taken after the injection of a specialized X-ray contrast dye.


The formation of new blood vessels, known as angiogenesis, plays a crucial role in facilitating the growth of tumors. Cancerous cells release specific chemicals called growth factors, which stimulate the development of fresh blood vessels in the vicinity of the tumor. These newly formed blood vessels serve to supply the tumor with essential nutrients and oxygen.


 


Posted

in

by

Tags: