Bone morphogenetic protein 2 (BMP‐2)

Polypeptide that belongs to the transforming growth factor beta (TGF‐β) superfamily of proteins. Like other BMPs, it plays an important role in the development of bone and cartilage. It is involved in the Hedgehog pathway, TGF‐β signaling pathway, and cytokine–cytokine receptor interaction, as well as cardiac cell differentiation and epithelial to mesenchymal transition.


 


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