Category: B
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Bone regeneration strategies
Use of polypeptide growth factors as mediators to promote osteoblast migration, mitogenesis, or matrix synthesis leading to bone regeneration.
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Bone regeneration
Renewal or repair of lost bone tissue. Also: Cellular events during wound healing; recapitulation of cellular events of embryogenesis. The quantitative extent is defect dependent and influenced by cellular race.
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Bone reduction guide
A stereolithographic guide used to assist in accurate reduction of excess bone in the mandible or maxilla.
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Bone quality
A qualitative assessment of bone based on its density.
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Bone preparation
Act of readying the bony site for implant, transplant, or graft placement. To achieve implant osseointegration, a low‐trauma preparation of the implant bed is necessary. Bone preparation with several drills of increasing diameter is performed using copious saline solution to provide cooling.
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Bone morphogenetic protein receptors (BMPR)
Transmembrane receptors that are present in a wide variety of cells and mediate BMP signals. They comprise serine or threonine kinase receptors composed of subtypes I and II.
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Bone morphogenetic protein 7 (BMP‐7)
Member of the transforming growth factor beta (TGF‐β) superfamily of proteins. Similar to other members of the BMP family of proteins, it plays a key role in the transformation of mesenchymal cells into bone and cartilage. It is inhibited by noggin. BMP‐7 may be involved in bone homeostasis and is expressed in the brain, kidneys,…
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Bone morphogenetic protein 5 (BMP‐5)
Polypeptide member of the transforming growth factor beta (TGF‐β) superfamily of proteins. BMP‐5 may play a role in certain cancers. Like other BMPs, BMP‐5 is inhibited by molecules chordin and noggin. It is expressed in the trabecular meshwork, lung, liver, and optic nerve, and may be involved in the development and normal function of these…
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Bone morphogenetic protein 4 (BMP‐4)
Polypeptide belonging to the transforming growth factor beta (TGF‐β) superfamily of proteins. Like other BMPs, it is involved in bone and cartilage development, specifically tooth and limb development and fracture repair, and has been shown to be involved in muscle development and bone mineralization.
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Bone morphogenetic protein 2 (BMP‐2)
Polypeptide that belongs to the transforming growth factor beta (TGF‐β) superfamily of proteins. Like other BMPs, it plays an important role in the development of bone and cartilage. It is involved in the Hedgehog pathway, TGF‐β signaling pathway, and cytokine–cytokine receptor interaction, as well as cardiac cell differentiation and epithelial to mesenchymal transition.