Category: C

The European Union’s (EU’s) scientific advisory organization dealing with approvals of new medicinal products intended use in animals. Its recommendations (e.g., to either approve, or not approve a new product) are usually adopted by the European Medicines Evaluation Agency (EMEA).  

The British Government agency that must approve new pharmaceutical products for sale within the United Kingdom. In concert with the Medicines Control Agency (MCA), it regulates all pharmaceutical products in the United Kingdom. It is the equivalent of the U.S. Food and Drug Administration. The official body which advises the British Government on the safety…

The European Union’s (EU’s) scientific advisory organization dealing with new human pharmaceuticals approval. Its recommendations (e.g., to either approve or not approve a new product) are usually adopted by the European Medicines Evaluation Agency (EMEA), to which the CPMP reports. Within 60 days of a CPMP “approval for recommendation” being adopted by the EMEA, each…

An agency of the French government, established to oversee and regulate all genetic engineering activities in the country of France.  

The site on an antibody molecule that locks (binds) onto an epitope (hapten).  

A term used to describe the set of technologies that are utilized to generate a large number of samples of (new) chemicals, which are then tested for potential use (e.g., for therapeutic effect, in the case of pharmaceutical). These large numbers of chemical samples, thus generated, are called a “library” and are screened (e.g., for…

A term used to describe the set of DNA technologies that are utilized to generate a large number of samples of new chemicals (metabolites) via creation of non-natural metabolic pathways. This collection of samples thus generated, is called a “library,” and the samples are then tested for potential use (e.g., for therapeutic effect, in the…

A technique using in situ hybridization to identify bacterial colonies carrying inserted DNA that is homologous with some particular sequence (probe).  

Proteins produced by Escherichia coli (E. coli), that are toxic (primarily) to other closely-related strains of bacteria. The particular E. coli that produce a given colicin are generally unaffected by the colicin that they produce.  

A process of acclimatization in which certain organisms produce specific proteins that protect them from freezing to death during the winter. Among other organisms, the common housefly, the fruit fly, and “no-see-em’s” (i.e., Culicoides variipennis) can produce these proteins (e.g., during the gradually decreasing temperatures of a typical fall season in North America). The amount…