Category: D
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DNA Ligase
An enzyme that creates a phosphodiester bond between the 3′ end of one DNA segment and the 5′ end of another, while they are base-paired to a template strand. The enzyme seals (joins) the ends of single-stranded DNA in a duplex DNA chain. DNA ligase constitutes a part of the DNA repair mechanism available to…
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Diversity biotechnology consortium
A nonprofit U.S. organization that was formed in August of 1 994 by a group of research institutions and companies. The Consortium’s first president is Stuart A. Kauffman of the Santa Fe Institute. The Consortium’s purpose is to further the use of molecular diversity as a tool in drug design and in the study of…
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Disulfide bond
An important type of covalent bond formed between two sulfur atoms of different cysteines in a protein. Disulfide bonds (hnkages, bridges) contribute to holding proteins together and also help provide the internal structure (conformation) of the protein. A covalent bond between two sulfur-containing amino acids, which helps maintain the shape of proteins such as insulin,…
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Dissimilation
The breakdown of food material to yield energy and building blocks for cellular synthesis.
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Diplophase
A phase in the life cycle of an organism in which the cells of the organism have two copies of each gene. When this state exists the organism is said to be diploid.
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Digestion (within organisms)
The enzyme-enhanced hydrolysis (breakdown) of major nutrients (food) in the gastrointestinal system to yield their building-block components (to the organism), such as amino acids, fatty acids, or other essential nutrients.
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Diastereoisomers
Four variations of a given molecule, consisting of a pair of stereoisomers about a second asymmetric carbon atom for each of the two isomers of the first asymmetric carbon atom.
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Dextrorotary (D) Isomer
A stereoisomer that rotates the plane of plane-polarized light to the right. Dextro = right.
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Dextran
A polysaccharide produced by yeasts and bacteria as an energy storage reservoir (analogous to fat in humans). Consists of glucose residues, joined almost exclusively by alpha-1,6 linkages. Occasional branches (in the molecule) are formed by alpha 1,2, alpha 1,3, or alpha 1,4 linkages. Which linkage is used depends on the species of yeast or bacteria…
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Desulfovibrio
A genus of bacteria that reduces sulfate to H2S (hydrogen sulfide). Energy is obtained by oxidation of H2 or organic molecules. Not a strict autotroph because CO2 cannot be used as a sole carbon source.