Category: D

A rare X-linked or autosomal dominant disease characterized by dystrophic formation of the nails, oral leukoplakia, and hyperpigmentation of the skin. Affected patients may also suffer bone marrow failure, resulting in aplastic anemia or pulmonary fibrosis.  

Epithelial alterations in which certain isolated malpighian cells become differentiated Keratinization abnormality refers to an atypical deposition of the tough protein keratin on the skin or nails. This condition can manifest in various forms, one of which stems from a rare, inherited disorder primarily associated with an X-linked recessive genetic trait. However, autosomal dominant and…

Abnormality of the nucleus of a cell. Dyskaryosis refers to abnormal alterations observed in the nuclei of cells, especially during the initial phases of cancer. This condition can be identified through microscopic analysis of cells, commonly performed in procedures like a cervical smear test.  

A hemoglobin derivative that is incapable of reversibly associating with oxygen, and so is unable to carry oxygen from the lungs to the cells. The primary defect in dyshemoglobins is a chemical (or stereochemical) alteration of the heme prosthetic group. Two common dyshemoglobins are carboxyhemoglobin (COHb) in which carbon monoxide is covalently bonded to the…

A functional disorder of the genital organs.  

Abnormality of the mandible and maxilla.  

Abnormality of the amount or quality of blood globulins.  

Disproportion in the concentration of immunoglobulins in the blood. It may be congenital or acquired.  

Hesitant or halting verbal or written language use. Examples of dysfluencies are cluttering and stuttering. This lack of linguistic fluency may be normal during the early phases of language acquisition (e.g., in childhood).  

Any anomaly in the molecular architecture of fibrinogen. It may cause abnormal bleeding, abnormal blood clotting, or both.