Category: I

A laboratory test used to identify antibody-bearing cells by the formation of rosettes composed of red blood cells and those cells bearing antibodies.  

A protein used in the laboratory to assess the number of immune complexes in blood, which may be related to immunological activity. It acts by binding with complement factor 3, a significant part of an antigen-antibody immune complex.  

The chemistry of antigens, antibodies, receptors, and other molecules involved in immunological reactions.  

The study of immune phenomena in biological systems, including the immune response to infectious diseases, transplantation of organs, allergy, autoimmunity, and cancer.  

Any substance derived from a pathogen that can immunize a person or a community against disease; e.g., a vaccine.  

Exposure to monoclonal antibodies in order to isolate specific analytes. Immunoaffinity purification is used during the preparation of blood products to reduce their likelihood of contamination by specific disease-causing microorganisms.  

A genetically engineered, antibody like protein that fuses the Fc region of an immunoglobulin and the ligand-binding region of a receptor or adhesion molecule. Immunoadhesins can be used to direct the immune-responsive effect of cytokines to tumor cells and to stimulate the destruction of such cells.  

The process by which the immune system destroys, dilutes, or walls off injurious agents and injured tissue. Small blood vessels dilate and become permeable. This increases blood flow and permits exudation of plasma and leukocytes. The cells arriving from the blood include monocytes, neutrophils, basophils, and lymphocytes; those of local origin include endothelial cells, mast…

An immune globulin preparation used intravenously in patients with immunodeficiency syndromes and in immunosuppressed recipients of bone marrow transplants. In conjunction with aspirin, it is the standard of care for children during the first 10 days of Kawasaki disease to prevent the development of coronary aneurysms.  

A preparation of immune globulin that is injected directly into a muscle. It can be used to provide passive immunity to a wide variety of infections including, for example, hepatitis A.