Category: L
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Leakage current
In electrosurgery current that flows toward a ground along a path that the surgeon did not intend.
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Lead optimization
The synthetic refinement of a candidate drug from its crude or original state into an agent that is safer, more useful, or more marketable.
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Lead molecule
A chemical compound thought to be useful, safe, and distinctive enough that it might prove to be a good candidate for drug development.
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Leading zero
A zero that precedes a decimal point, e.g., as in “levothyroxine 0.5 mg p.o. daily.” Leading zeros should always be employed when writing prescriptions for doses of drugs that are fractions of a unit. In the example above an alternative method of writing the drug dose without decimals is “levothyroxine 50 gg p.o. daily.”
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Lead pipe contraction
Cataleptic condition during which limbs remain in any position in which placed.
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Lead monoxide
A reddish-brown compound used to prepare lead subacetate.
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Lead acetate
A lead compound that is used in solution as an astringent.
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Leaching
Extraction of a substance from a mixture by washing the mixture with a solvent in which only the desired substance is soluble.
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Leachate
A contaminated liquid that leaves soil after water percolates through earth (e.g., in waste disposal sites), farmlots, or landfills.
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Lazarus sign
Dramatic movements of the arms across the torso, which are occasionally observed in brain-dead patients after they have been disconnected from mechanical life support. These movements may be misinterpreted as signs of life, when in fact they are merely involuntary reflexes,