Category: M
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Microaerophile
An organism that grows best in the presence of a small amount of oxygen.
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Methylated
Refers to a DNA molecule that is saturated with methyl groups (i.e., methyl submolecule groups, βCH3, have attached themselves to the DNA molecule at all possible locations). Generally, when a DNA molecule is methylated, the genes comprising that DNA molecule are “turned off” (i.e., inactivated).
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Membrane transport
The facilitated transport of a solute across a membrane, usually by a specific membrane protein (e.g., adhesion molecule).
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Melting temperature (of DNA) (Tm)
The midpoint of the temperature range over which DNA is denatured.
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Melting (of substance other than DNA)
To change from a solid to a nonsolid (e.g., liquid) state by the addition of heat (to the solid substance).
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Melting (of DNA)
Melting DNA means to heat-denature it. When this happens the hydrogen bonds holding the DNA molecule together in the normal way are disrupted, allowing a more random polymer structure to exist.
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Mega-yeast artificial chromosomes (mega YAC)
A large (i.e., greater than 500 base pairs in length) piece of DNA that has been cloned (made) inside a living yeast cell. While most bacterial vectors cannot carry DNA pieces that are larger than 50 base pairs, and “standard” YACs typically cannot carry DNA pieces that are larger than 500 base pairs, mega YACs…
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Megakaryocyte stimulating factor (MSF)
A colony stimulating factor (protein) involved in the regulation of platelet production, white blood cell production, and red blood cell production from stem cells in bone marrow.
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Medium
A substance used to provide nutrients for cell growth. It may be liquid (e.g., broth) or solid (e.g., agar). Pertaining to the middle. The substance or material in which anything moves or acts. Average, in the middle or at the halfway point. Substance through which something moves or acts. A contrast medium, for example, has…
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Medicines control agency (MCA)
The British Government agency that, in concert with the Committee on Safety in Medicines, regulates the approval and sale of pharmaceutical products in the United Kingdom. An executive agency of the Department of Health with the prime function of safeguarding the public health.