Category: T

Schools selected for special programs, notably to receive federal monies under Chapter 1.  

A child who has unusual talents, deficiencies, socioeconomic disadvantage, troubled home situation, or some other special characteristics outlined by a program designed to help children, such as Head Start, a child abuse and neglect prevention program, or screening for programs under the Education for All Handicapped Children Act of 1975 or the Gifted and Talented…

The ability to use communication skills.  

Tuberous sclerosis is a dominantly inherited syndrome, with onset in the first decade of life, characterized pathologically by the presence of hamartomas in multiple organ systems. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the widespread development of distinctive tumors termed hamartomas. The clinical features of epilepsy, learning difficulties, and skin signs…

Trisomy 18 or Edwards syndrome, named for the researcher who first identified it, is an autosomal dominant chromosome ab¬ normality. The autosomes are the 22 pairs of non-sex chromosomes. A dominant gene is a gene that overrides the normal copy from the partner and has a 50% chance of being passed on. There are three…

Tricho-rhino-phalangeal syndrome (TRP) is a genetic ectodermal dysplastic disorder affecting multiple systems. Three types have been distinguished. All three types, however, share a common set of characteristic physical anomalies.  

Thalidomide was among the first drugs identified as a teratogen, a chemical agent that can cross the placenta and cause congenital malformations to the developing embryo and fetus. Effective as a sedative and a tranquilizer, thalidomide had positive effects on the mother but devastating consequences for the embryo.  

Thalassemia is a blood disorder of genetic origin that results from the interaction of thalassemia genes and those genes associated with abnormal hemoglobins. Heterozygous thalassemia or thalassemia minor is the less serious form of the disorder and is generally without symptoms. Homozygous thalassemia or thalassemia major is the more serious form of the disorder and…

Deficiency in tetrahydrobiopterin (BH4) is a rare genetic disorder due to a defect in metabolism of amino acids. BH4 impairs the metabolism of enzymes resulting in hyper-phenylalanimia and a defect of neurotransmitter synthesis. Clinical manifestations are similar and usually indistinguishable from classic phenylketonuria (PKU). In most cases of BH4, progressive neurological symptoms appear between the…

Tethered spinal cord syndrome occurs when the spinal cord does not hang freely in the spinal canal but instead is attached at the coccyx. It has a variety of identifying characteristics, including external manifestations such as lipomas or fatty tumors, skin tags, sacral dimple, benign tumors composed of blood vessels, excessive growth of hair in…