Chemokines

Are chemotactic cytokines, which stimulate migration of inflammatory cells towards tissue sites of inflammation.


Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: C (chemokines, C), CC (chemokines, CC), and CXC (chemokines, CXC), according to variations in a shared cysteine motif.


Any polypeptide cytokine that causes chemotaxis, attracting neutrophils, monocytes, and T lymphocytes; e.g., to assist in destroying an invading microorganism.


 


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