An empirical methodology utilized to (inexpensively) infer a chemical quantity/value from (indirect) measurement(s) of other physical/chemical values (which can be obtained inexpensively). The term chemometrics was coined in 1975 by Bruce Kowalski. One example of the use of chemometrics is to infer the TME(N) or “true metabolizable energy” of high-oil com from that corn’s protein and oil (fat) content.