Sterile plasma obtained by pooling approximately equal amounts of citrated whole blood from eight or more healthy persons. The plasma is separated from the blood cells, sterility tests are made, a preservative is added, and the plasma is bottled. It may then be kept as a liquid at a temperature between 2° and 5°C., frozen by rapid freezing, or dried in a high vacuum at temperatures below freezing point. All three forms can be stored for a very long time. Plasma can be used for all the purposes for which whole blood is employed, except the restoration of hemoglobin. Since human plasmas are rarely incompatible with each other, they can be used in an emergency to restore the blood volume very rapidly and without much preliminary blood testing, as opposed to blood transfusion, which requires special tests to insure that the blood to be administered is compatible with that of the patient.