Coagulation

The process of changing liquid to solid, especially of blood; clotting.


In colloid chemistry, the solidification of a sol into a gelatinous mass; an alteration of a disperse phase or of a dissolved solid which causes the separation of the system into a liquid phase and an insoluble mass called the clot or curd. Coagulation is usually irreversible.


In surgery, the disruption of tissue by physical means to form an amorphous residuum, as in electrocoagulation and photocoagulation.


Aprocess involving the denaturation of proteins, so that they become insoluble; it may be effected by heat, strong acids and alkalis, metals, and other chemicals. The final stage in blood clotting is the precipitation of insoluble fibrin, formed from the soluble plasma protein fibrinogen.


The process by which a colloidal liquid changes to a jellylike mass.


Coagulation of the blood is the process whereby bleeding (or haemorrhage) is normally arrested in the body. Blood starts to clot as soon as the skin (or other tissue) has been cut. Coagulation is part of the process of haemostasis which is the arrest of bleeding from an injured or diseased blood vessel. Haemostasis depends on the combined activities of vascular, platelet and plasma elements which are offset by processes to restrict the accumulation of platelets and fibrin to the damaged area.


The thickening of a liquid into a gel or solid.


 

 

 

 

 


Posted

in

by

Tags: