Coenzyme A

A water-soluble vitamin known as pantothenic acid. A coenzyme in all living cells. It is required by certain condensing enzymes and functions in acyl-group transfer and in fatty-acid metabolism. Abbreviated CoA.


A complex molecule containing pantothenic acid is required for fatty acid oxidation and synthesis, and for the synthesis of cholesterol and phospholipids combines with acetate, and which, in turn, combines with oxaloacetate to form citrate and enter the tricarbolic acid cycle coenzyme.


Coenzyme A is a pantothenic acid containing coenzyme important in the activation of acyl compounds. CoA forms a thioester bond with acetyl and acyl groups and with amino acids and facilitates their metabolism.


Coenzyme A (CoA) is a molecule produced in part by pantothenic acid, which is part of its structure. The main functions of coenzyme A are to act as a donor and acceptor of acyl groups (such as fatty acids, etc.). For example, coenzyme A can accept or donate an acetyl group and in those capacities is critical for metabolic processes such as the Krebs cycle, beta-oxidation, fatty acid and cholesterol synthesis, and more.


A nucleotide containing pantothenic acid, which is an important coenzyme in the Krebs cycle and in the metabolism of fatty acids.


A derivative of pantothenic acid, important as a carrier molecule for acetyl groups in many reactions including the Krebs cycle and the oxidation of fatty acids.


 


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