A molecule characterized by a triple helical structure and a high content of glycine, proline, and hydroxyproline. It is the major constituent of connective tissue fibers, the organic matrix of bone, dentin, cementum, and basal laminas. Collagen is synthesized by fibroblasts, chondroblasts, osteoblasts, and odontoblasts. Several types are found in the human body. Type 1 collagen is one of the first products synthesized by the body when bone formation occurs.
Protein that is the major constituent of cartilage and other connective tissue; comprises the amino acids hydroxyproline, proline, glycine, and hydroxylysine.
A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of skin, connective tissue, and the organic substance of bones and teeth. Different forms of collagen are produced in the body but all consist of three alpha-polypeptide chains arranged in a triple helix. Collagen is differentiated from other fibrous proteins, such as elastin, by the content of proline, hydroxyproline, and hydroxylysine; by the absence of tryptophan; and particularly by the high content of polar groups which are responsible for its swelling properties.
Insoluble protein in connective tissue, bones, tendons, and skin of animals and fish; converted into the soluble protein, gelatine, by moist heat.
Insoluble animal protein found in connective tissues. Collagen can be converted to gelatin with moist heat.
The major structural protein in connective tissue. It is instrumental in wound healing [stimulated by fibroblast growth factor (FGF), platelet-derived growth factor, and insulin-like growth factor- 1].
The main supportive and connective tissue in the body. It forms the basic structure for tendons, ligaments, skin, and cartilage.
The main supportive and connective tissue in the body. It forms the basic structure for tendons, ligaments, skin, and cartilage.
A comparatively insoluble protein that is found in the skin, tendons, bones, and cartilage is converted to gelatin by boiling.
A thick protein fibre forming bundles, which make up the connective tissue, bone and cartilage.
The main organic constituent of connective tissue and of the organic substance of bones: changed into gelatin by boiling.
An important component of connective tissues, including the veins and arteries that carry nutrients to the brain.
A fibrous protein that is found in skin, bone, and connective tissue.
The principle structural protein of bones, teeth, skin, cartilage, tendons, cornea, and blood vessels. Rich in proline and hydroxyproline. The synthesis of collagen in vivo is dependent on adequate intakes of vitamin C. Collagen, when boiled, becomes partly soluble. The soluble portion can be separated from the insoluble portion and when separated is known as gelatin. Gelatin is deficient in tryptophan and thus is a poor-quality dietary protein.
A strong, fibrous protein that is the major component of connective tissue. Connective tissue, which includes tendons, ligaments, organ walls, blood vessels, cartilage, and the soft inner material of the bone, requires collagen for strength and elasticity. Collagen is also the component of s car tissue that holds a wound together to promote healing and prevent infection. Vitamin C is important in the production of collagen.
A protein that is the principal constituent of white fibrous connective tissue (as occurs in tendons). Collagen is also found in skin, bone, cartilage, and ligaments. It is relatively inelastic but has a high tensile strength.
The most abundant protein in the body. It is the major structural component of many parts of the body and occurs in many different forms. Thus it exists as thick fibres in skin and tendons. It is also an important constituent of the heart and blood vessels. With calcium salts it provides the rigid structure of bone. It also occurs as a delicate structure in the cornea of the eye, and in what is known as the basement membrane of many tissues including the glomeruli of the kidneys and the capsule of the lens of the eye. It plays a part in many diseases, hereditary and otherwise. Among the inherited abnormalities of collagen are those responsible for aneurysms of the circle of willis and for osteogenesis imperfecta. On boiling it is converted into gelatin.
A strong, fibrous insoluble protein found in connective tissue, including the dermis, tendons, ligaments, deep fascia, bone, and cartilage. Collagen is the protein typical of dental tissues (except enamel), forming the matrix of dentin, cementum, and alveolar bone proper. Collagen fibers also form the periodontal ligament, which attaches the teeth to their bony sockets.
Fibrous protein that gives the skin form and strength.
A protein consisting of bundles of tiny fibers that forms connective tissue including the white inelastic fibers of the tendons, ligaments, bones, and cartilage.
A proteinaceous fiber discovered predominantly in cutaneous, osseous, cartilaginous, tendinous, dental, and vascular tissues.
The principal structural protein found in cartilage, connective tissue, tendons, skin, and bones, providing essential support and integrity.
Collagen, a resilient and fibrous protein, serves as the primary structural protein in the human body. It plays a vital role in the composition of tendons, bones, and connective tissue.