Duodenal ulcer

An ulcer in the duodenum.


Ulcer in the duodenum; it is the most common type of peptic ulcer.


A sore or wound in the mucous membrane lining the wall of the duodenum, the first part of the small intestine into which the contents of the stomach are emptied. Nine of ten duodenal ulcers develop on the duodenal bulb, the first part of the duodenum. Although variable in size, they are usually less than one-half inch wide. Men are more likely than women to develop duodenal ulcers.


An ulcer in the duodenum, caused by the action of acid and pepsin on the duodenal lining (mucosa) of a susceptible individual. It is usually associated with an increased output of stomach acid and affects people with blood group O more commonly than others. Symptoms include pain in the upper abdomen, especially when the stomach is empty, which often disappears completely for weeks or months; vomiting may occur. Complications include bleeding, ‘perforation, and obstruction due to scarring. Symptoms are relieved by antacid medicines or reduction of stomach acid; surgery is sometimes required for a permanent cure.


This disorder is related to gastric ulcer, both being a form of chronic peptic ulcer. Although becoming less frequent in western communities, peptic ulcers still affect around 10 per cent of the UK population at some time in their lives. Duodenal ulcers are 10—15 times more common than gastric ulcers.


An open sore on the mucosa of the first portion of the duodenum, most often the result of infection with Helicobacter pylori. It is the most common form of peptic ulcer.


A break in the lining (mucosa) of the duodenum caused by the action of acid digestive juices.


An unhealed region in the wall of the duodenum (the initial segment of the small intestine) occurs as a result of wear and tear to its internal lining. Duodenal and gastric (pertaining to the stomach) ulcers are both variants of peptic ulcer, and share commonalities in their origins, signs, and therapeutic approaches.


A duodenal ulcer, often linked to stress and prevalent among those prone to worry, manifests as a recurring upper-abdominal pain that typically arises post-meal and initially subsides upon further eating. This discomfort can interrupt sleep in the early morning hours and, while it may seem to temporarily abate, allowing for normal eating, it tends to escalate to continuous pain over time. The intermittent nature of the pain leads to misleading claims of cure by over-the-counter remedies, as patients may prematurely attribute their pain-free phases to such treatments, although these periods are a natural part of the condition’s cycle and not due to the medication. Such testimonials, often used in advertising, conveniently omit any later complications like hemorrhages. Medical management includes administering antacids, ensuring the patient eats regularly or takes medication every two hours, consuming bedtime olive oil to reduce acid, providing sedatives, and employing psychotherapy to reduce stress. Surgical approaches have evolved from bypass techniques to partial gastrectomy and duodenectomy, and now include sewing the ulcer shut and severing the nerve to the duodenum. In the U.S., there’s an experimental procedure where the duodenum is frozen using a specialized tube to promote healing.


 


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