Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
The protein that enables the blood to clot.
A blood protein converted into fibrin by the enzyme thrombin.
A substance in blood plasma which produces fibrin when activated by thrombin.
The precursor of fibrin that provides a network of fibers that forms the structural element in clot formation.
Protein present in the blood plasma and essential to the process of blood coagulation; the factor (Factor I) converted into fibrin by thrombin in the presence of calcium ions during the process of blood coagulation.
A substance (coagulation factor), present in blood plasma, that is acted upon by the enzyme thrombin to produce the insoluble protein fibrin in the final stage of ‘blood coagulation. The normal level of fibrinogen in plasma is 2-4 g/1.
The soluble protein in the blood which is the precursor of fibrin, the substance in blood clot.
A protein, also called factor I, synthesized by the liver and present in blood plasma that is converted into fibrin through the action of thrombin in the presence of calcium ions. Fibrin forms the clot.
A blood protein that engages in interaction with thrombin to generate fibrin, an essential component involved in blood clot formation.
Fibrinogen is a protein found in the blood that transforms into fibrin during the blood clotting process.
The substance that precedes fibrin in the blood. During blood clotting, thrombin transforms fibrinogen into fibrin when calcium and thromboplastin are present.
A portion of regular human plasma, when dissolved, possesses the ability to transform into soluble fibrin upon the addition of thrombin. It is administered through intravenous infusion to enhance the blood’s coagulation capability.