Fox-Fordyce disease

A chronic pruritic papular eruption of areas of the skin that contain apocrine sweat glands. The intraepidermal ducts of the apocrine glands become obstructed and eventually rupture. The disease occurs mostly in persons 13 to 35 years of age and about 10 times more frequently in women than men. It does not occur before puberty.


A long-lasting condition characterized by itching, typically seen in women, which is marked by the presence of tiny bumps in areas where apocrine sweat glands are situated.


The bumps associated with Fox-Fordyce disease result from blockage and bursting of apocrine ducts in the epidermis, the skin’s outermost layer. Utilizing topical retinoids, which are derivatives of vitamin A, and antibiotics can potentially alleviate symptoms in patients who have been experiencing the disease over an extended period.


 


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