A type of goitre in middle-aged women, where the woman is sensitive to secretions from her own thyroid gland, and, in extreme cases, the face swells and the skin turns yellow [Described 1912. After Hakuru Hashimoto (1881-1934), Japanese surgeon.]
An autoimmune disease of the thyroid gland. The gland is enlarged with a firm goitrous appearance. The individual (usually female) is either euthyroid or hypothyroid with a mild myxedematous look. Thyroglobulin antibodies are of the IgG type, and complexes of the hormone and these antibodies are frequently deposited in the gland.
Autoimmune disorder of the thyroid gland, most common in middle-aged women, in which antibodies are produced against thyroid tissue. Symptoms include an enlarged, lumpy thyroid gland. Treatment is by administration of thyroid hormones.
Chronic inflammation of the thyroid gland (thyroiditis) due to the formation of antibodies against normal thyroid tissue (autoantibodies). Its features include a firm swelling of the thyroid and partial or total failure of secretion of thyroid hormones; often there are autoantibodies to other organs, such as the stomach.
condition in which the whole of the thyroid gland is diffusely enlarged and firm. It is one of the diseases produced by autoimmunity. The enlargement is due to diffuse infiltration of lymphocytes and an increase of fibrous tissue. This form of goitre appears in middle-aged women, does not give rise to symptoms of thyrotoxicosis, and tends to produce myxoedema.
Hashimoto’s disease, the leading cause of primary hypothyroidism, is an autoimmune disorder. It holds the distinction of being the first recognized autoimmune disease. The name of the condition originates from Hakaru Hashimoto, a Japanese physician who first documented it in 1912.
Persistent inflammation of the thyroid gland.