Lack of normal tone in the large intestine, resulting in decreased contractions and propulsive movements, delay m the normal passage of material through the intestine to the anus, often an enlargement of the colon, and constipation. It may be congenital (e.g., Hirsch-sprung’s disease) or acquired (e.g., through inadequate food and fluid intake, faulty elimination habits, intake of certain drugs, certain diseases). Treatment includes efforts to establish regular elimination habits, use of stool softeners and agents to increase fecal bulk, and a diet containing adequate bulk and fluids.