The administration of parenteral medications such as insulin into a different part of the body each day to avoid local tissue trauma, atrophy, or lipodystrophies. Subcutaneous injections of insulin are typically rotated around the abdomen from the right upper quadrant, to the midepigastrium, left upper quadrant, left lower quadrant, hypogastrium, and right lower quadrant before returning to the right upper quadrant. A similar technique is used with low-molecular weight heparins, colony-stimulating factors, and other drugs