Itraconazole

An antifungal agent that has been used in the treatment of histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis.


An antifungal drug used to treat serious fungal infections, particularly of the lungs. Itraconazole (Sporanox) is used to prevent and treat the fungal infections histoplasmosis and blastomycosis; both are diseases of the lung. A liquid form of the drug is used to treat candidiasis (thrush) in the mouth or throat. It has also been used to treat fungal infections of the nails. Itraconazole is also available in capsule form to treat oral candidiasis and fungal infections of the nails.


A triazole antifungal drug taken by mouth for candida (thrush) infection in the mouth or female genitalia, the skin condition pityriasis versicolor, and tinea corporis and tinea pedis (athlete’s foot). It is also used for widespread fungal infections such as aspergillosis, candidiasis and cryptococcosis where other fungicidal drugs have not worked. Itraconazole is metabolized in the liver so should not be given to patients who have or have had liver disease. The drug can be given as maintenance treatment of AIDS patients to prevent resurgence of underlying fungal disease to which they are especially vulnerable.


 


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