Platelet aggregation

The attachment of platelets to one another. This clumping together can be induced by a number of agents (e.g., thrombin, collagen) and is part of the mechanism leading to the formation of a thrombus.


Platelets are the small, rather uniform fragments of large bone marrow cells that aid the blood in coagulation, hemostasis, inflammation, and thrombus formation. Mild subclotting and sticking is a common early condition that can lead to thrombosis, atherosclerosis, and strokes, and can be helped by an aspirin a day, better fat digestion, and Red Root.


A test done on blood to evaluate blood clotting capacity. Excess clotting time indicates a blood clotting deficit, blood disorder, or the presence of drugs that delay normal clotting of blood.


The aggregation of blood cells, potentially resulting in the formation of a clot.


Platelet aggregation refers to the process of platelets, which are small and adhesive blood particles, clumping together. This phenomenon occurs when a blood vessel sustains damage. It serves as the initial phase of blood clotting, aiding in the formation of a plug to seal the injured vessel. Platelet aggregation plays a crucial role in maintaining the integrity of the circulatory system when vessels are compromised.


Excessive or inappropriate platelet aggregation can give rise to detrimental consequences. In the case of arterial involvement, it can lead to thrombosis, wherein a blood clot forms within an intact blood vessel. To address this issue, various medications are available, such as aspirin and clopidogrel, which work to mitigate platelet aggregation. These drugs play a crucial role in reducing the risk of unwanted clotting events and promoting optimal blood flow through the arteries.


The aggregation of platelets as a part of a sequential process that leads to the beginning and development of a thrombus or a hemostatic plug.


 


Posted

in

by

Tags: