A condition in which there are multiple cysts on each kidney which grow and multiply over time.
Polycystic kidney diseases are genetic disorders characterized by the presence of multiple fluid-filled cysts in both kidneys. The number of cysts present can vary from few to many, depending on the individual. The cysts range in size and become larger as the disease progresses.
Abnormal condition in which the kidneys are enlarged and contain many cysts. It occurs in childhood and adult forms and often leads to kidney failure.
An inherited disorder characterized by deformed nephrons that develop multiple grapelike cysts throughout the kidneys; requires dialysis and kidney transplant.
An inherited disorder in which the kidneys are enlarged and contain clusters of fluid-filled cysts. Polycystic kidney disease may produce only a few small cysts or many cysts. Over time, the cysts tend to destroy kidney tissue, eventually leading to kidney failure.
An inherited disease in which the kidneys contain many cysts. These grow in size until normal kidney tissue is largely destroyed. Cysts may also occur in other organs such as the liver. In adults, the disease will cause hypertension and kidney failure. There is also a juvenile form. There is no effective treatment, although symptoms can be alleviated by dialysis and sometimes kidney transplant.
An inherited renal disorder transmitted as an autosomal recessive trait in infants and as an autosomal dominant trait in adults. PKD was previously termed adult polycystic kidney disease. It is characterized by cyst formation in ductal organs, particularly the kidney and liver, and by gastrointestinal and cardiovascular abnormalities. Included are colonic diverticula, cardiac valvular abnormalities, and intracranial and aortic aneurysms. Symptoms include hypertension, acute and chronic pain, and urinary tract infections. It is one of the most common hereditary disorders, occurring in about 1 in 400 to 1 in 1000 people. An estimated 500,000 persons have the disease in the U.S. It accounts for 10% of cases of end-stage renal disease. Treatment includes medical therapy for renal failure with eventual renal dialysis and renal transplantation.
Any of several hereditary disorders in which cysts form in the kidneys and other organs, eventually destroying kidney tissue and function. The autosomal recessive form usually appears in early childhood; the autosomal dominant form usually develops later in life. Definitive treatments are dialysis and kidney transplant. Because cerebral aneurysms are commonly found in adults with PKD, patients with this disorder are often screened with computed tomography or magnetic resonance imaging studies of the brain.
Polycystic kidney disease is an inherited renal disorder characterized by the development of fluid- or blood-filled sacs called cysts on the tubules of the kidneys. These cysts interfere with the normal functioning of the kidneys, leading to impaired kidney function.