Protease inhibitors

Compounds which inhibit or antagonize biosynthesis or actions of proteases (endopeptidases).


Compounds that inhibit the protein degradative action of the protease enzymes.


Class of anti-HIV (Human Immunodeficiency Virus) drugs designed to inhibit the enzyme protease and interfere with virus replication. Protease inhibitors prevent the cleavage of HIV precursor proteins into active proteins, a process that normally occurs when HIV replicates; used in therapy of AIDS and HIV infection.


A drug class used to treat AIDS (acquired immunodeficiency syndrome). Protease inhibitors work by suppressing the ability of HIV (human immunodeficiency virus) to reproduce. Protease inhibitors are always used in combination with other AIDS drugs and sometimes with other protease inhibitors. It is important for protease inhibitors to be taken exactly as prescribed, because drug resistance can develop very quickly in HIV. People with AIDS should never use protease inhibitors alone, and they should never miss doses or days of therapy.


A group of drugs which, in combination with antiviral agents, are used to treat AIDs. They inhibit the activity of protease, an enzyme produced by HIV, and which breaks down proteins. The drugs in use include indinavir, nelfinavir, ritonavir and saquinavir.


A substance that inhibits the action of enzymes.


A medication used to combat HIV, which hinders an essential enzyme necessary for the replication of the virus.


An antiretroviral medication employed to slow down the advancement of HIV infection.


 


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