When rats and some humans are fed sucrose-rich, low-fat diets, blood lipids, particularly triacylglycerols, increase. This is due to the fact that the fructose of the sucrose is metabolized primarily by the liver, and the product of this metabolism is triacylglyceride, which is then exported to the periphery for storage. In normal individuals, there is adaptation to this diet and the lipemia subsides.