The end-product of purine metabolism.
The final end product of certain proteins in the body or from the diet, especially the nucleoproteins found in the nucleus of cells. Unlike the much smaller protein waste product urea, which is mostly recycled to form many amino acids, uric acid is an unrecyclable metabolite. It is a bent nail that won’t restraighten, and it must be excreted nucleoprotein to purine to uric acid to the outside in the urine or the sweet.
A nitrogenous end product of purine metabolism is present in the blood and excreted in the urine. An accumulation of may contribute to the development of gout.
A chemical compound which is formed from nitrogen in waste products from the body and which also forms crystals in the joints of people who have gout.
Crystalline acid, excreted in urine, from purine metabolism.
Product of protein metabolism present in the blood and excreted in urine. Deposits of uric acid and its salts occur in gout.
An end product of protein metabolism that is present in measurable quantities and ultimately excreted in urine.
A substance elevated in the serum and urine in various diseases such as gout, and decreased if the patient is taking anticoagulants or antiworm medication.
An organic acid containing nitrogen; the by-product of nucleic acid metabolism and a component of blood and urine. Normal amounts of uric acid are eliminated from the body in urine, but high amounts of uric acid can form solid crystals. If these solid crystals lodge in the joints and skin, they can cause a painful condition called gout. Uric acid crystals that form in the kidneys can cause kidney stones. Large amounts of uric acid are found in certain foods, particularly red meats, organ meats such as liver and kidney, anchovies, and some shellfish.
A nitrogen-containing organic acid that is the end-product of nucleic acid metabolism and is a component of the urine. Crystals of uric acid are deposited in the joints of people suffering from gout.
A crystalline acid, C5H4N403, occurring as an end product of purine metabolism. It is formed from purine bases derived from nucleic acids (DNA and RNA). It is a common constituent of urinary stones and gouty tophi.
Uric acid, a metabolic byproduct resulting from the breakdown of purines, is eliminated from the body through the kidneys. Elevated levels of uric acid, often attributed to various medical conditions, can contribute to the development of kidney stones. These crystalline formations within the kidneys can arise due to the excessive accumulation of uric acid, leading to discomfort, pain, and potential complications. Managing uric acid levels and addressing the underlying causes are essential in mitigating the risk of kidney stone formation and maintaining overall urinary health.
Uric acid, a byproduct resulting from the decomposition of nucleic acids within bodily cells, is also generated in minor quantities during the digestion of nucleic acid-rich foods like liver, kidney, and other organ meats. The majority of uric acid produced in the body is directed towards the kidneys, which eliminate it through urine. However, a portion enters the intestines, where it undergoes further breakdown into substances that are eventually expelled in the feces.
When the process of uric acid excretion faces disruption, such as due to kidney disease, it can lead to a condition called hyperuricemia—characterized by elevated levels of uric acid in the bloodstream. This, in turn, could potentially trigger the development of gout or kidney stones.
In primates, the final product of breaking down purines is urate, which has a notably low solubility in water. Issues with purine metabolism can lead to gout, a condition characterized by the accumulation of sodium urate crystals in joints and skin, triggering an inflammatory response as if reacting to a foreign object.