Vinca alkaloids

A group of powerful cytotoxic (anticancer) drugs used to treat acute leukaemia lymphoma and some solid tumours such as breast and lung cancers. Originally derived from the periwinkle plant, the latest vinca alkaloid (vinorelbine) is a semi-synthetic drug. These alkaloids, which are given intravenously, have potentially serious side-effects on the nervous system and also suppress the production of myeloid cells in the bone marrow.


A drug made from vinca plants and used in cancer therapy.


A collection of compounds sourced from the periwinkle plant (VINCA ROSEA) are employed in the treatment of various medical conditions. These substances are particularly effective in addressing conditions like leukemias (blood cancers), lymphomas (cancers originating in lymphoid tissue), and certain types of solid tumors such as breast cancer and lung cancer.


Neurological toxicity is a potential outcome of using any vinca alkaloid, manifesting as neuropathy or nerve damage. Additional side effects might encompass abdominal discomfort, constipation, and reversible alopecia, which refers to temporary hair loss. Examples of widely recognized vinca alkaloids comprise vinblastine, vindesine, and vincristine.


 


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