Von willerbrands disease

Von Willerbrands disease (VWD) is a common, mild type of congenital coagulopathy (bleeding disorders; Miller, Pearson, Baehner, & McMillan, 1978). VWD is thought to be associated with an X-linked autosomal dominant genetic disorder leading to a deficiency in the soluble clotting Factor VIII (antihemophilic factor) complex responsible for coagulatory responses. The prevalence of VWD has been approximated at 1% of the general population (Type I). Type HI VWD, the most severe type, has an approximate prevalence of 1 in 1,000,000 births.


 


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