Wilms tumor

Wilms tumor (also known as nephroblastoma) is a malignant renal tumor and is the second most common extracranial solid tumor in children. In 80-90% of the cases, it occurs in the renal blastoma tissue. It usually is characterized by an asymptomatic abdominal mass and abdominal swelling.


Malignant neoplasm of the kidney, occurring in young children; symptoms include hypertension, followed by pain, blood in the urine, and presence of a palpable mass. Treatment includes surgery, irradiation, and chemotherapy.


A rapidly developing malignant neoplasm of the kidney of unknown etiology, seen in infants and children before age five; it may be treated with surgery, radiation, or chemotherapy.


A cancerous tumor of the kidneys that occurs mainly in children. Wilms tumor is the most common type of kidney tumor in children; the cause is not known. The tumor may develop in fetal tissue, but the peak incidence is in 3-year-olds. It is associated with certain congenital defects such as urinary tract abnormalities and enlargement of one side of the body. There is an increased incidence of Wilms tumor among siblings and twins, and there may be a contributing genetic factor. Although it generally remains localized, the tumor can become large and spread to other tissues. It is usually diagnosed through ultrasound scanning. Treatment may require radical nephrectomy.


A rapidly developing tumor of the kidney that usually occurs in children. It is the most common renal tumor of childhood. It is associated with chromosomal deletions, especially from chromosomes 11 and 16. In the past, the mortality from this type of cancer was extremely high; however, newer approaches to therapy have been very effective in controlling the tumor in about 90% of patients.


A cancerous growth found in the kidney, typically seen in early childhood.


 


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