1.0Glossaryhttps://www.healthbenefitstimes.com/glossaryGlossaryhttps://www.healthbenefitstimes.com/glossary/author/adminglossary/Coffin–Siris syndrome - Definition of Coffin–Siris syndromerich600338<blockquote class="wp-embedded-content" data-secret="DeEEiHn1Qz"><a href="https://www.healthbenefitstimes.com/glossary/coffin-siris-syndrome/">Coffin–Siris syndrome</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.healthbenefitstimes.com/glossary/coffin-siris-syndrome/embed/#?secret=DeEEiHn1Qz" width="600" height="338" title="“Coffin–Siris syndrome” — Glossary" data-secret="DeEEiHn1Qz" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script>
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This autosomal genetic disorder is characterized by the absence or underdevelopment of the distal parts of the little finger and little toe. Additional features may include hirsutism (excessive hair growth), hypotonia (reduced muscle tone) and joint laxity, as well as learning difficulties.