1.0Glossaryhttps://www.healthbenefitstimes.com/glossaryGlossaryhttps://www.healthbenefitstimes.com/glossary/author/adminglossary/rich600338<blockquote class="wp-embedded-content" data-secret="MvIJd0mVqb"><a href="https://www.healthbenefitstimes.com/glossary/endocannabinoids/">Endocannabinoids</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.healthbenefitstimes.com/glossary/endocannabinoids/embed/#?secret=MvIJd0mVqb" width="600" height="338" title="“Endocannabinoids” — Glossary" data-secret="MvIJd0mVqb" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://www.healthbenefitstimes.com/glossary/wp-includes/js/wp-embed.min.js </script> Endogenous lipid-based retrograde neurotransmitters in cannabis plant that bind to cannabinoid receptors in the human body.Compounds involved in feeding behavior and body weight regulation. They are arachidonic acid derivatives that are synthesized when needed. They bind to CB1 receptors and are rapidly degraded. The endocannabinoid system normally functions to increase food intake and energy storage. The system consists of two types of cannabinoid receptors, CB1 and CB2. CB1 receptors are present in many central and peripheral sites involved in the control of energy homeostasis (e.g., brain, adipose tissue, gastrointestinal tract, liver, and muscle). CB2 receptors are primarily expressed in the immune system and do not appear to play a major role in energy homeostasis or food intake. Both receptors are G-protein-coupled receptors whose primary function is to transduce specific extracellular stimuli into intracellular signals. In turn, these signals modulate glucose homeostasis, hepatic lipogenesis, and adipose tissue metabolism. In the adipose tissue, stimulation of CB1 receptors has been shown to increase the lipoprotein lipase expression, down regulate adiponectin and reduce the expression of AMP kinase.Any chemical produced by the body that stimulates receptors for Cannabis sativa in the central nervous system.