1.0Glossaryhttps://www.healthbenefitstimes.com/glossaryGlossaryhttps://www.healthbenefitstimes.com/glossary/author/adminglossary/rich600338<blockquote class="wp-embedded-content" data-secret="L9KDunoXiF"><a href="https://www.healthbenefitstimes.com/glossary/folacin/">Folacin</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.healthbenefitstimes.com/glossary/folacin/embed/#?secret=L9KDunoXiF" width="600" height="338" title="“Folacin” — Glossary" data-secret="L9KDunoXiF" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://www.healthbenefitstimes.com/glossary/wp-includes/js/wp-embed.min.js </script> An older term for the B vitamin folic acid or folate. Folacin plays an important role in cell reproduction and has a protective effect against a variety of disorders, especially birth defects. Good sources of folacin include dried beans and peas, green vegetables, oranges, whole grains, and fortified grain products.A member of the vitamin B complex group is necessary for cell growth and reproduction. A deficiency can result in megaloblastic anemia is a water-soluble vitamin.An essential B vitamin that participates in one-carbon transfer. Folic acid (folate or folacin) is the generic term for pteroylmonoglutamic acid and its related biologically active compounds. A number of derivatives have vitamin activity. The derivatives include the addition of hydrogen at N5 and N10 and only one glutamate attached to para-aminobenzoic acid. This derivative is called tetrahydrofolic acid (THF). Other derivatives can have a methyl group attached at N5, a methyl bridge between N5 and NIO or a methylene bridge at this position or an aldehyde group at either N5 or N10 or a HCNH group at N5. All of these derivatives have vitamin activity because vitamin activity is dependent on the presence of a pterin structure with variable hydrogenation or methyl addition at N5 or N10 and the presence of at least one glutamyl residue linked via peptide bonds to p-aminobenzoic acid. Methotrexate (4-amino-N10-methyl folic acid, an antineoplastic agent) and aminopterin (4-amino folic acid, a rodenticide) are folate antagonists and as such are useful pharmaceutical agents against cell growth. Folacin is an orange-yellow crystal with a melting point of 250°C. It is unstable to ultraviolet light, heat, oxygen, acid conditions, and divalent metal ions such as iron and copper.