1.0Glossaryhttps://www.healthbenefitstimes.com/glossaryGlossaryhttps://www.healthbenefitstimes.com/glossary/author/adminglossary/rich600338<blockquote class="wp-embedded-content" data-secret="oAyHXNmKCw"><a href="https://www.healthbenefitstimes.com/glossary/genetic-probe/">Genetic probe</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.healthbenefitstimes.com/glossary/genetic-probe/embed/#?secret=oAyHXNmKCw" width="600" height="338" title="“Genetic probe” — Glossary" data-secret="oAyHXNmKCw" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://www.healthbenefitstimes.com/glossary/wp-includes/js/wp-embed.min.js </script> Fluorescence in situ hybridization (FISH) testing. A test of DNA (deoxyribonucleic acid) designed to identify the presence of genetic defects in a person or, usually, a fetus. In a genetic probe, a particular fragment of DNA is examined for genetic markers, specific base sequences (chemical configurations) that have been associated with a genetic defect. Genetic probes can be used to detect the presence of Down syndrome, cystic fibrosis, trisomy 21 syndrome, and such chromosomal abnormalities as Turner syndrome.A particular segment of DNA is employed in laboratory examinations to ascertain the presence of a specific genetic defect within an individual's DNA. This segment, known as the "probe," possesses an identical structure to the abnormal gene. When introduced to a sample of the person's DNA, the probe will attach itself to the gene if it is present. To facilitate easy detection, a radioactive or fluorescent marker can be incorporated into the probe.Genetic probes find primary application in antenatal diagnosis of genetic disorders, as well as in identifying whether individuals with a family history of such disorders harbor the faulty gene themselves.