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</html><description>The earliest example of a patent medicine containing opium was first concocted by Paracelsus in the early part of the sixteenth century. Thomas Sydenham is also credited with its development, but it was somewhat different in its ingredients. A more powerful mixture was compounded by Thomas Dover in 1732, known as Dover&#x2019;s powder.A solution of opium in alcohol that was formerly in widespread use for pain relief.A hydroalcoholic solution containing 1% morphine, prepared from nucerated raw opium. It was formerly widely used as a narcotic analgesic, taken by mouth.A solution derived from opium was once used as a sedative, pain reliever, and for treating diarrhea.</description></oembed>
