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</html><description>An invasion of the dermis and subcutaneous fat by leukemic cells. The invasion often happens before these cells proliferate in the bone marrow or are detectable in the peripheral blood. The cells may cause several different types of skin rashes, including blue nodules (giving the skin a &#x201C;blueberry muffin&#x201D; appearance), papules, plaques, and ulcers.</description></oembed>
