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</html><description>A pervasive developmental disorder and genetic condition characterized by the appearance, between ages 5 months and 48 months, of decelerated head growth, loss of previously acquired purposeful hand movements and development of stereotyped hand movements (hand wringing), loss of social engagement (social interaction may develop later), poorly coordinated gait or trunk movements, and impaired expressive and receptive language with severe psychomotor retardation.</description></oembed>
