{"version":"1.0","provider_name":"Glossary","provider_url":"https:\/\/www.healthbenefitstimes.com\/glossary","author_name":"Glossary","author_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/","title":"DNA Probe - Definition of DNA Probe","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"iMv4x2yd2D\"><a href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/dna-probe\/\">DNA Probe<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.healthbenefitstimes.com\/glossary\/dna-probe\/embed\/#?secret=iMv4x2yd2D\" width=\"600\" height=\"338\" title=\"&#8220;DNA Probe&#8221; &#8212; Glossary\" data-secret=\"iMv4x2yd2D\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.healthbenefitstimes.com\/glossary\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"Also called gene probe or genetic probe. Short, specific (complementary to desired gene) artificially produced segments of DNA used to combine with and detect the presence of specific genes (or shorter DNA segments) within a chromosome. If a DNA probe of known composition and length is mingled with pieces of DNA (genes) from a chromosome, the probe will cling to its exact counterpart in the \"chromosomal DNA pieces\" (genes), forming a stable double-stranded hybrid. The presence of this (now) \"labeled\" probe is detected visually or with the aid of another detection instrument. Because the composition of the DNA probes is known, scientists can riffle through a chromosome, spotting segments of DNA (i.e., genes) that seem to be linked to genetic diseases.A single-strand DNA fragment used to detect the complementary fragment. DNA probes are used widely in bacteriology. Recombinant DNA techniques are used to isolate, reproduce, and label a portion of the genetic material, DNA, from the nucleus of a microorganism that is specific for it. This fragment can be added to a specimen containing the organisms. The specimen and known DNA are treated so that the DNA strands from the organisms in the specimen are separated into single strands. The DNA from the specimen rejoins (is annealed to) the known labeled DNA and is thereby labeled. This permits the identification of a single pathogenic organism in a specimen that contains many different microorganisms.An agent that possesses the ability to directly attach or bind to a predetermined sequence of nucleic acids."}